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 smoking slows down your brain

 

 

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In their 9thyear in the study, participants completed the MicroCog Assessment of Cognitive Function, a well-established standard group of tests that assess short-term memory, immediate and delayed story recall, verbal analogies, mathematical reasoning and visual-spatial processing.

 

Scores for each test, and a global proficiency score, are based on the accuracy and speed of a person's responses, adjusted for education level and age. The participants also took a short form of the standard IQ test, and their scores were adjusted for age.

40 of the men had clinically diagnosable alcoholism at the time of the test, though none had been drinking within an hour of the tests. 24 of these men also were smokers. The study also included sixty three men who had had alcoholism earlier in life, twenty-nine of whom smoked; and sixty-nine men who had never been alcoholic, thirteen of whom smoked. All smokers were allowed to smoke at any time during the testing session, so none were in a nicotine-deprived state when they took the neurocognitive tests.

Glass and her colleagues analyzed the participants' scores using 2 standard measures of long-term smoking and drinking behavior: lifetime alcohol problem severity, or LAPS, and pack-years, a measure that takes into account the number of packets of cigarettes a person smoked each day and the number of years they smoked that much.

Across the board, both drinking and smoking showed an effect: Higher pack-years and LAPS scores were both significantly associated with lower global cognitive proficiency scores and IQ.

When the researchers limited the analysis to those participants who had ever had a diagnosis of alcoholism during their lifetime, they still found a significant association between LAPS scores and IQ, and between pack-years and both IQ and overall cognitive proficiency. In fact, the impact of heavy lifetime smoking history was greater than the effect of lifetime drinking history.

This finding, Glass says, means that alcoholism researchers who have consistently found evidence of cognitive deficits among alcoholics — but who have not taken smoking into account in their analysis — may actually be seeing a combined effect of smoking and alcohol consumption among alcoholic study participants who smoke. Further analyses of these data, with smoking separated out as a variable just as hard drug use is often separated, is needed, she says.

Glass, who also holds positions in the University of Michigqan's Institute for Social Research and Chronic Pain & Fatigue Research Center, co-authored the paper with Zucker, and with Kenneth Adams, Ph.D., a professor of psychology in psychiatry at U-M and chief of the psychology service at VAAAHCS; Maria Wong, Ph.D., Anne Buu, Ph.D., Jennifer Jester, Ph.D., and Leon Puttler, Ph.D., of UMARC; and Joel Nigg, Ph.D., and Hiram Fitzgerald, Ph.D., of MSU.

 

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